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Purified Diet (= Open Source Diet)

조성표 자체가 공개되어 있으며, 정제된 원료를 사용한 식이입니다.
Chlorophyl-free diet로 in vivo imaging 연구에 용이합니다.

Obesity and Diabetes

The Original High Fat Diet

품명(열량 대비 %)	Type	중량(kg)	단가/kg (부가세별도)	납기
Rodent Diet with 10%Kcal Fat	Pellet	1kg 단위	30,000원	2일
Rodent Diet with 45%Kcal Fat
Rodent Diet with 60%Kcal Fat		1~49kg	25,000원
		50kg~	23,000원

기본 조제사료 가격표

품명	Type	중량(kg)	단가/kg	납기
AIN-76A Purified Rodent Diet	Pellet	1~50 kg	35,000원	2일
AIN-76A Purified Rodent Diet	Pellet	51kg~	30,000원	2일
AIN-93G Purified Rodent Diet	Pellet	1kg	70,000원	2일
AIN-93M Purified Rodent Diet	pellet/powder	12.5kg 이상	수량에 따른 변동	약 6~8주

Obesity

Genetic and environmental factors play a role in the development of obesity, and diet is one of the main environmental factors that contributes to this disease. Human studies have shown that increased fat intake is associated with body weight gain which can lead to obesity and other related metabolic diseases. Animal rodent models are therefore useful tools for studying obesity as they will readily gain weight when fed high-fat diets

Diabetes / Insulin Resistance

Effect of High Fructose/Sucrose Diets on Plasma
Lipid Levels and Insulin Resistance in Rodents

Atherosclerosis

D12336 (Purified diet matched to Paigen diet)
D12079B (Western Diet)

Hypertension

Historically, the preferred small animal model for hypertension research has been the rat. is may be due to the amount of published physiological data, relative small size, and robust responses seen in some genetic strains. Because of the polygenic nature of hypertension, numerous rat models have been developed including selective bred homozygous hypertensive rat strains (e.g. spontaneously hypertensive rat [SHR] and Dahl salt sensitive [Dahl SS]) and outbred strains (e.g. Sprague Dawley) to elucidate the desired hypertensive phenotype. As the form of hypertension can differ between strains, researchers need to not only be aware of the form of hypertension that the individual strain exhibits but also the impact that a particular type of diet may have on the phenotypic response.

Fatty Liver Disease

As with most human diseases driven by diet, fatty liver in rodents is also diet-inducible. Different dietary approaches (likely working by different mechanisms) are available and so researchers should be aware of the advantages and disadvantages of each. Here we briefly summarize three such protocols for inducing fatty liver: feeding a methionine and choline-deficient (MCD) diet, a choline-deficient diet (CD) or a high-fat diet (HFD). Of course, each of these terms does not define a specific diet formula, and the researcher should be aware that there are many variations of each of these diet groups which can have different effects on the phenotype of the animal.

Cancer

Laboratory animal models are important tools in oncology research, as they allow scientists to test their in vitro-generated hypotheses in a mammalian, whole-animal system. Since many types of cancer can be affected by environmental factors, having control over these factors is key to generating reproducible, meaningful data. Research Diets products are routinely used for oncology research. OpenSource diets contain purified ingredients provide a clean background (i.e. phytoestrogen and cholorphyll-free) to reduce ‘noise’ during in vivo imaging, and easily control for factors that may impact gene expression.

Test Compounds in Diets

Chemotherapeutics, COX-2 Inhibitors, Antioxidants, Nutraceuticals, Statins, Insulin sensitizers, NSAIDS, Doxycycline 등

Immunology

Gene Expression

Doxycycline Diet
Tetracycline-based externally regulated (Tet-based) systems are a powerful tool to study temporal expression of transgenes in vivo. Research Diets can incorporate Doxycycline into your existing purified diet or chow, providing combined genotypic and phenotypic control. Doxycycline in pelleted diet offers increased photo-stability for consistent dosing. Available in resealable vacuum packed foil bags for added protection.

Pelleted Diets Reduce Labor
Precision doxycycline supplemented diets offer significant advantages over water delivery. Combining the pelleted diet with automated watering systems can save time and reduce labor. This product is sold only for use in animal research to be conducted only under the supervision of a licensed veterinarian. Veterinary authorization is required.